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The Science of Aging - Volume II


3 causes of sagging skin

And how to prevent it!

3 causes of sagging skin

And how to prevent it

3 causes of sagging skin

And how to prevent it !

Cause #1:Oxidative Stress
Just by going outside, we’re exposing our skin to a wide variety of damaging factors that lead to skin deterioration. Environmental agents like pollution, low air humidity and cigarette smoke generate free radicals in the skin which damages both the skin’s epidermal and dermal cells, contributing to their degeneration. As the cells lose their ability to function normally, the elastic fibers in our skin (collagen, elastin, laminin and fibronectin) are degraded, which results in wrinkles, dehydration, loss of volume and yes … sagging.

Cause #1:Oxidative Stress
Just by going outside, we’re exposing our skin to a wide variety of damaging factors that lead to skin deterioration. Environmental agents like pollution, low air humidity and cigarette smoke generate free radicals in the skin which damages both the skin’s epidermal and dermal cells, contributing to their degeneration. As the cells lose their ability to function normally, the elastic fibers in our skin (collagen, elastin, laminin and fibronectin) are degraded, which results in wrinkles, dehydration, loss of volume and yes … sagging.

Cause #2: Infra-Aging
The fact that sun exposure is directly related to skin aging is nothing new, but did you know that scientists estimate that the sun is responsible for 90% of premature skin aging? For many years sun-induced aging, also known as photo aging was solely attributed to UV rays. More recently however, it has been found that infrared (IR) rays and the heat they generate, greatly affects the quality of the skins elastic fibers and alters dermal structural proteins, leading to premature skin aging, loss of elasticity and the subsequent sagging.

Cause #1:Oxidative Stress
Just by going outside, we’re exposing our skin to a wide variety of damaging factors that lead to skin deterioration. Environmental agents like pollution, low air humidity and cigarette smoke generate free radicals in the skin which damages both the skin’s epidermal and dermal cells, contributing to their degeneration. As the cells lose their ability to function normally, the elastic fibers in our skin (collagen, elastin, laminin and fibronectin) are degraded, which results in wrinkles, dehydration, loss of volume and yes … sagging.

Cause #2: Infra-Aging
The fact that sun exposure is directly related to skin aging is nothing new, but did you know that scientists estimate that the sun is responsible for 90% of premature skin aging? For many years sun-induced aging, also known as photo aging was solely attributed to UV rays. More recently however, it has been found that infrared (IR) rays and the heat they generate, greatly affects the quality of the skins elastic fibers and alters dermal structural proteins, leading to premature skin aging, loss of elasticity and the subsequent sagging.

Cause #2: Infra-Aging
The fact that sun exposure is directly related to skin aging is nothing new, but did you know that scientists estimate that the sun is responsible for 90% of premature skin aging? For many years sun-induced aging, also known as photo aging was solely attributed to UV rays. More recently however, it has been found that infrared (IR) rays and the heat they generate, greatly affects the quality of the skins elastic fibers and alters dermal structural proteins, leading to premature skin aging, loss of elasticity and the subsequent sagging.

Cause #3: Natural Aging

Nothing reflects the passing of time more accurately than our own skin. As our body functions change with aging, these changes directly affect the appearance of our skin:

  • Loss of fat below the skin in the cheeks, temples, chin, nose and eyes result in the loosening of our skin.
  • The reduction of bone mass around the mouth and chin causes our skin to droop, as well as puckering around the mouth area.
  • As the skin loses elasticity, gravity causes the skin around the cheeks and jaw to droop and sag.

Fighting and Preventing Sagging Skin

Looking closely, we can see that all 3 causes have the same effect in our skin: the deterioration of the skin’s elastic fibers. The good news is, there’s something we can do about it.

1.- Condition the skin cells that produce collagen elastin,lamining & fibronectin.

2.- Maintain the integrity of the skin by boosting the production of collagen, laminin, fibronectin and elastin

3.- Protect the elastic fibers from degradation

Cause #3: Natural Aging

Nothing reflects the passing of time more accurately than our own skin. As our body functions change with aging, these changes directly affect the appearance of our skin:

  • Loss of fat below the skin in the cheeks, temples, chin, nose and eyes result in the loosening of our skin.
  • The reduction of bone mass around the mouth and chin causes our skin to droop, as well as puckering around the mouth area.
  • As the skin loses elasticity, gravity causes the skin around the cheeks and jaw to droop and sag.

Fighting and Preventing Sagging Skin

Looking closely, we can see that all 3 causes have the same effect in our skin: the deterioration of the skin’s elastic fibers. The good news is, there’s something we can do about it.

1.- Condition the skin cells that generate collagen elastin,lamining & fibronectin.

2.- Maintain the integrity of the skin by boosting the production of collagen, laminin, fibronectin and elastin

3.- Protect the elastic fibers from degradation


The ideal anti-sagging regime should include breakthrough anti-aging ingredients to achieve these 3 objectives in a systematic way:

The ideal anti-sagging regime should include breakthrough anti-aging ingredients to achieve these 3 objectives in a systematic way:


The ideal anti-sagging regime should include breakthrough anti-aging ingredients to achieve these 3 objectives in a systematic way:

RxG302™
A patented cellular extract evolved from the 2012 Nobel Prize Award winning technology, RxG302™ has the ability to condition skin cells to perform at their peak, providing the ideal environment for other advanced ingredient to promote the natural production of collagen, laminin, fibronectin and elastin

RxG302™
A patented cellular extract evolved from the 2012 Nobel Prize Award winning technology, RxG302™ has the ability to condition skin cells to perform at their peak, providing the ideal environment for other advanced ingredient to promote the natural production of collagen, laminin, fibronectin and elastin

ChroNOline™
A high-tech biomimetic peptide designed for optimal skin penetration. ChroNOline™ boosts the production of key components of the DEJ (Collagen VII, Laminin-5, fibronectin) for optimal skin structural support, reducing the appearance of wrinkles and sagging.

ChroNOline™
A high-tech biomimetic peptide designed for optimal skin penetration. ChroNOline™ boosts the production of key components of the DEJ (Collagen VII, Laminin-5, fibronectin) for optimal skin structural support, reducing the appearance of wrinkles and sagging.

Elix-IR™
Elix-IR™ is the first botanical active ingredient designed to specifically target Infra’Aging™ (infrared-induced skin aging) and to protect elastic fibers of papillary and reticular dermis from sun damage in order to prevent premature aging appearing after repeated sun exposure. UV and IR penetrate dermis with a different depth but both affect the quality of elastic fibers. Cathepsin G is an enzyme highly present in photoaged skin and has for consequence of inducing an increase of MMP synthesis responsible for dermis fiber degradation. By inhibiting Cathepsin G activity, Elix-IR™ protects tropoelastin and fibrillin-1, the main components of the elastic fibers distributed in papillary dermis (upper dermis) and in reticular dermis (lower dermis).

In Summary

When it comes to sagging skin, protecting the collagen and elastic fibers in the skin is key.

The not-so-good news... Technology has not yet found a way to completely stop degradation of th elastic fibers and the subsequent skin sagging.

The great news... New technologies like cellular extracts (RxG302, ChoNOline and ElixIR) now allow us to not only condition the skin cells, but also boost the production of collagen, elastin, laminin and fibronectin, as well as protect them against accelerated degradation. This results in the reversal of the skin's sagging process. Products like RxGenesys that are able to maintain cells, boost the production of collagen and protect the elastic fibers from degradation have been clinically proven to improve firmness and elasticity by 43% in only 2 months.

Dr. Jeffrey Gibson, an American plastic surgeon specialized in cell regeneration & rejuvenation and co-founder of RxGenesys, is the first doctor to put together in one daily beauty routine, all the recommended ingredients to reverse the sagging process in the skin. Additionally it's surprisingly affordable and is clinically tested.

As a plastic surgeon, Dr Gibson believes in making decisions based on scientific data and proof. That’s why (unlike other companies) we make our complete clinical study reports available for anyone to see on our website (https://rxgenesys.com/pages/results):

RxGenesys is proven to:

  • Reduce the appearance of wrinkles by 53% in 2 months
  • Improve firmness and elasticity by 43% in 2 months
  • 100% of participants noticed a visible reduction in their fine lines and wrinkles

ElixIR™
Elix-IR™ is the first botanical active ingredient designed to specifically target Infra’Aging™ (infrared-induced skin aging) and to protect elastic fibers of papillary and reticular dermis from sun damage in order to prevent premature aging appearing after repeated sun exposure. UV and IR penetrate dermis with a different depth but both affect the quality of elastic fibers. Cathepsin G is an enzyme highly present in photoaged skin and has for consequence of inducing an increase of MMP synthesis responsible for dermis fiber degradation. By inhibiting Cathepsin G activity, Elix-IR™ protects tropoelastin and fibrillin-1, the main components of the elastic fibers distributed in papillary dermis (upper dermis) and in reticular dermis (lower dermis).

Cause #3: Natural Aging
Nothing reflects the passing of time more accurately than our own skin. As our body functions change with aging, these changes directly affect the appearance of our skin:

  • Loss of fat below the skin in the cheeks, temples, chin, nose and eyes result in the loosening of our skin.
  • The reduction of bone mass around the mouth and chin causes our skin to droop, as well as puckering around the mouth area.
  • As the skin loses elasticity, gravity causes the skin around the cheeks and jaw to droop and sag.

RxG302™
A patented cellular extract evolved from the 2012 Nobel Prize Award winning technology, RxG302™ has the ability to condition skin cells to perform at their peak, providing the ideal environment for other advanced ingredient to promote the natural production of collagen, laminin, fibronectin and elastin

ChroNOline™
A high-tech biomimetic peptide designed for optimal skin penetration. ChroNOline™ boosts the production of key components of the DEJ (Collagen VII, Laminin-5, fibronectin) for optimal skin structural support, reducing the appearance of wrinkles and sagging.

ElixIR™
Elix-IR™ is the first botanical active ingredient designed to specifically target Infra’Aging™ (infrared-induced skin aging) and to protect elastic fibers of papillary and reticular dermis from sun damage in order to prevent premature aging appearing after repeated sun exposure. UV and IR penetrate dermis with a different depth but both affect the quality of elastic fibers. Cathepsin G is an enzyme highly present in photoaged skin and has for consequence of inducing an increase of MMP synthesis responsible for dermis fiber degradation. By inhibiting Cathepsin G activity, Elix-IR™ protects tropoelastin and fibrillin-1, the main components of the elastic fibers distributed in papillary dermis (upper dermis) and in reticular dermis (lower dermis).

In Summary

When it comes to sagging skin, protecting thde collagen and elastic fibers in the skin is key.

The not-so-good news... Technology has not yet found a way to completely stop degradation of th elastic fibers and the subsequent skin sagging.

The great news... New technologies like cellular extracts (RxG302, ChoNOline and ElixIR) now allow us to not only condition the skin cells, but also boost the production of collagen, elastin, laminin and fibronectin, as well as protect them against accelerated degradation. This results in the reversal of the skin's sagging process. Products like RxGenesys that are able to maintain cells, boost the production of collagen and protect the elastic fibers from degradation have been clinically proven to improve firmness and elasticity by 43% in only 2 months.

Dr. Jeffrey Gibson, an American plastic surgeon specialized in cell regeneration & rejuvenation and co-founder of RxGenesys, is the first doctor to put together in one daily beauty routine, all the recommended ingredients to reverse the sagging process in the skin. Additionally it's surprisingly affordable and is clinically tested.

As a plastic surgeon, Dr Gibson believes in making decisions based on scientific data and proof. That’s why (unlike other companies) we make our complete clinical study reports available for anyone to see on our website (https://rxgenesys.com/pages/results):

RxGenesys is proven to:

  • Reduce the appearance of wrinkles by 53% in 2 months
  • Improve firmness and elasticity by 43% in 2 months
  • 100% of participants noticed a visible reduction in their fine lines and wrinkles

It's all about the results