The Science of Aging - Volume I
4 Types of wrinkles
and how to fight them!
Wrinkles!!!! We all have them, and most of us hate them. Understanding why they appear in the first place is the first step to successfully fighting these annoying signs of aging
4 Types of wrinkles
and how to fight them!
Wrinkles!!!! We all have them, and most of us hate them. Understanding why they appear in the first place is the first step to successfully fighting these annoying signs of aging
4 Types of wrinkles
and how to fight them!
Wrinkles!!!! We all have them, and most of us hate them. Understanding why they appear in the first place is the first step to successfully fighting these annoying signs of aging
The 4 main types of wrinkles:
1. Dynamic Expresion Lines
These are the “good kind" of wrinkles, they appear temporarily while making facial expressions
Where do they Appear?
Typically appear in the forehead, around the eye and in the area between the nose and the mouth (nasolabial fold)
What Causes them?
They are caused by the movement of the muscles of the face, which results in a fold. Expressive people will tend to show more of them; the good news is that they are entirely normal, the bad news is that with time they tend to become Static Wrinkles
How to fight them?
The best you can do to fight the effects of dynamic expression lines is to keep your skin hydrated and keep the elastic fibers conditioned to avoid their structural breakdown. Ingredients such as
Hyaluronic Acid, Vitamin E and Peptides are the first line of defense. But if you are the kind of person that would rather take more radical preventive measures, you can always opt in for compounds that temporarily paralyze the muscle, like Botox™
1. Dynamic Expresion Lines
These are the “good kind" of wrinkles, they appear temporarily while making facial expressions
Where do they Appear?
Typically appear in the forehead, around the eye and in the area between the nose and the mouth (nasolabial fold)
What Causes them?
They are caused by the movement of the muscles of the face, which results in a fold. Expressive people will tend to show more of them; the good news is that they are entirely normal, the bad news is that with time they tend to become Static Wrinkles
How to fight them?
The best you can do to fight the effects of dynamic expression lines is to keep your skin hydrated and keep the elastic fibers conditioned to avoid their structural breakdown. Ingredients such as
Hyaluronic Acid, Vitamin E and Peptides are the first line of defense. But if you are the kind of person that would rather take more radical preventive measures, you can always opt in for compounds that temporarily paralyze the muscle, like Botox™
2. Static Wrinkles
Are the Are the folds and lines that are present even when we’re not forming facial expressions.
Where do they Appear?
Just like the dynamic expression lines, they typically appear in the forehead, around the eye and in the area between the nose and the mouth (nasolabial fold)
What Causes them?
They are the result of dynamic expression lines over time. The constant movement of the muscle of the face will eventually result in the degradation of the elastic fibers of the skin in the fold area. Just like a piece of plastic, when bent back and forth, the area in the junction will tend to soften to allow for easier fold, creating a natural line.
How to fight them?
There are several ways to fight this kind of wrinkles, which can be used simultaneously.
a.- The use of neuro-calming drugs such as Botox™
b.- The conditioning and protection of the elastic fibers of the skin with peptides such as
ChronNOline™
c.- Dermal injectables designed to fill wrinkles is a more invasive (but temporary) solution
Natural Growth factors like ChroNOline™ boost the production of collagen, elastin, and fibrillin in the skin, which are the key structural components of the DEJ (dermal/epidermal junction) the place where wrinkles are created.
The use of compounds like botox will paralyze the muscles for an average period of 6 months allowing the skin the recover and rebuild the elastic fibers in the fold.
Using both solutions at the same time, allows your skin to rebuild its elastic fibers in an ideal environment, with zero muscle movement or friction
1. Dynamic Expresion Lines
These are the “good kind" of wrinkles, they appear temporarily while making facial expressions
Where do they Appear?
Typically appear in the forehead, around the eye and in the area between the nose and the mouth (nasolabial fold)
What Causes them?
They are caused by the breakdown of collagen due to UV exposure, smoking or environmental aggressors and pollutants, all of which act as a catalyst for free radical damage. For more on Oxidative damage visit
The International Dermal Institute
How to fight them?
The best you can do to fight the effects of dynamic expression lines is to keep your skin hydrated and keep the elastic fibers conditioned to avoid their structural breakdown. Ingredients such as
Hyaluronic Acid, Vitamin E and Peptides are the first line of defense. But if you are the kind of person that would rather take more radical preventive measures, you can always opt in for compounds that temporarily paralyze the muscle, like Botox™
2. Static Wrinkles
Are the Are the folds and lines that are present even when we’re not forming facial expressions.
Where do they Appear?
Just like the dynamic expression lines, they typically appear in the forehead, around the eye and in the area between the nose and the mouth (nasolabial fold)
What Causes them?
They are the result of dynamic expression lines over time. The constant movement of the muscle of the face will eventually result in the degradation of the elastic fibers of the skin in the fold area. Just like a piece of plastic, when bent back and forth, the area in the junction will tend to soften to allow for easier fold, creating a natural line.
How to fight them?
There are several ways to fight this kind of wrinkles, which can be used simultaneously.
a.- The use of neuro-calming drugs such as Botox™
b.- The conditioning and protection of the elastic fibers of the skin with peptides such as
ChronNOline™
c.- Dermal injectables designed to fill wrinkles is a more invasive (but temporary) solution
Natural Growth factors like ChroNOline™ boost the production of collagen, elastin, and fibrillin in the skin, which are the key structural components of the DEJ (dermal/epidermal junction) the place where wrinkles are created.
The use of compounds like botox will paralyze the muscles for an average period of 6 months allowing the skin the recover and rebuild the elastic fibers in the fold.
Using both solutions at the same time, allows your skin to rebuild its elastic fibers in an ideal environment, with zero muscle movement or friction
2. Static Wrinkles
Are the Are the folds and lines that are present even when we’re not forming facial expressions.
Where do they Appear?
Just like the dynamic expression lines, they typically appear in the forehead, around the eye and in the area between the nose and the mouth (nasolabial fold)
What Causes them?
They are the result of dynamic expression lines over time. The constant movement of the muscle of the face will eventually result in the degradation of the elastic fibers of the skin in the fold area. Just like a piece of plastic, when bent back and forth, the area in the junction will tend to soften to allow for easier fold, creating a natural line.
How to fight them?
There are several ways to fight this kind of wrinkles, which can be used simultaneously.
a.- The use of neuro-calming drugs such as Botox™
b.- The conditioning and protection of the elastic fibers of the skin with peptides such as
ChronNOline™
c.- Dermal injectables designed to fill wrinkles is a more invasive (but temporary) solution
Natural Growth factors like ChroNOline™ boost the production of collagen, elastin, and fibrillin in the skin, which are the key structural components of the DEJ (dermal/epidermal junction) the place where wrinkles are created.
The use of compounds like botox will paralyze the muscles for an average period of 6 months allowing the skin the recover and rebuild the elastic fibers in the fold.
Using both solutions at the same time, allows your skin to rebuild its elastic fibers in an ideal environment, with zero muscle movement or friction
3. Atrophic Crinkling
Is the accumulation of multiple parallel lines on the face and neck, generally are not very deep and tend todisappear as soon as the skin is stretched horizontally
Where do they Appear?
Atrophic Crinkling can appear anywhere in the body, but typically are the most visible in the forehead and chest.
What Causes them?
They are caused by the breakdown of collagen due to UV exposure, smoking or environmental aggressors and pollutants, all of which act as a catalyst for free radical damage. For more on Oxidative damage visit
The International Dermal Institute
How to fight them?
The best solution for this kind of wrinkle is a three-prong approach.
- Use SPF protection EVERY DAY!
- Prevent and fight free radical damage with powerful antioxidants such as Vitamin C and Green Tea extract
- Protect collagen and other elastic fibers from breaking down by inhibiting the degrading effects Capthesin-G with ingredients such as ElixIR™
4. Gravitational folds
These are those wrinkles that appear naturally with age as our skin loses firmness and starts to fold and sag
Where do they Appear?
Gravitational folds appear mostly in the face and neck area, especially where skin and bone density is lost due to age. Leaner faces will tend to make this kind of fold more apparent.
What Causes them?
Age, gravity and time are the main culprits. As we grow old, the skin loses volume and collagen, giving way to sagging skin which causes this type of wrinkle.
How to fight them?
- Intense anti-aging serums, hydrating creams, and beauty protocols, proven to improve firmness and elasticity are indispensable to reduce and reverse the appearance of this kind of wrinkles.
- New cellular extracts such as RxG302™ are now available in the USA. they have the ability to condition the skin at a cellular level, promoting the natural production of Collagen, Laminin and Fibrillin, while improving the cell’s ability to absorb the benefits of other anti-aging ingredients. Products with this kind of technology, like RxGenesys have already shown remarkable results in scientific clinical studies.
- As skin starts to lose volume and fold, the use of dermal fillers can help compensate for such loss, creating volume and making gravitational folds less apparent.
In Summary
When it comes to wrinkles, prevention and maintenance is the key to having and keeping a young and healthy looking skin.
The not-so-good news... Technology has not yet found a way to completely stop wrinkles from appearing or entirely erasing them once they are visible.
The great news... New technologies like cellular extracts (RxG302, ChoNOline and ElixIR) now allow us to significantly reduce the appearance of wrinkles NO MATTER THE AGE.
Dr. Jeffrey Gibson, an American plastic surgeon specialized in cell regeneration & rejuvenation and co-founder of RxGenesys, is the first doctor to put together in one daily beauty routine, all the recommended ingredients to target the different types of wrinkles and sagging skin. Additionally it's surprisingly affordable and is clinically tested.
As a plastic surgeon, Dr Gibson believes in making decisions based on scientific data and proof. That’s why (unlike other companies) we make our complete clinical study reports available for anyone to see on our website (https://rxgenesys.com/pages/results):
RxGenesys is proven to:
- Reduce the appearance of wrinkles by 53% in 2 months
- Improve firmness and elasticity by 43% in 2 months
- 100% of participants noticed a visible reduction in their fine lines and wrinkles
3. Atrophic Crinkling
Is the accumulation of multiple parallel lines on the face and neck, generally are not very deep and tend todisappear as soon as the skin is stretched horizontally
Where do they Appear?
Atrophic Crinkling can appear anywhere in the body, but typically are the most visible in the forehead and chest.
What Causes them?
They are caused by the breakdown of collagen due to UV exposure, smoking or environmental aggressors and pollutants, all of which act as a catalyst for free radical damage. For more on Oxidative damage visit
The International Dermal Institute
How to fight them?
The best solution for this kind of wrinkle is a three-prong approach.
- Use SPF protection EVERY DAY!
- Prevent and fight free radical damage with powerful antioxidants such as Vitamin C and Green Tea extract
- Protect collagen and other elastic fibers from breaking down by inhibiting the degrading effects Capthesin-G with ingredients such as ElixIR™
3. Atrophic Crinkling
Is the accumulation of multiple parallel lines on the face and neck, generally are not very deep and tend todisappear as soon as the skin is stretched horizontally
Where do they Appear?
Atrophic Crinkling can appear anywhere in the body, but typically are the most visible in the forehead and chest.
What Causes them?
They are caused by the breakdown of collagen due to UV exposure, smoking or environmental aggressors and pollutants, all of which act as a catalyst for free radical damage. For more on Oxidative damage visit
The International Dermal Institute
How to fight them?
The best solution for this kind of wrinkle is a three-prong approach.
- Use SPF protection EVERY DAY!
- Prevent and fight free radical damage with powerful antioxidants such as Vitamin C and Green Tea extract
- Protect collagen and other elastic fibers from breaking down by inhibiting the degrading effects Capthesin-G with ingredients such as ElixIR™
4. Gravitational folds
These are those wrinkles that appear naturally with age as our skin loses firmness and starts to fold and sag
Where do they Appear?
Gravitational folds appear mostly in the face and neck area, especially where skin and bone density is lost due to age. Leaner faces will tend to make this kind of fold more apparent.
What Causes them?
Age, gravity and time are the main culprits. As we grow old, the skin loses volume and collagen, giving way to sagging skin which causes this type of wrinkle.
How to fight them?
- Intense anti-aging serums, hydrating creams, and beauty protocols, proven to improve firmness and elasticity are indispensable to reduce and reverse the appearance of this kind of wrinkles.
- New cellular extracts such as RxG302™ are now available in the USA. they have the ability to condition the skin at a cellular level, promoting the natural production of Collagen, Laminin and Fibrillin, while improving the cell’s ability to absorb the benefits of other anti-aging ingredients. Products with this kind of technology, like RxGenesys have already shown remarkable results in scientific clinical studies.
- As skin starts to lose volume and fold, the use of dermal fillers can help compensate for such loss, creating volume and making gravitational folds less apparent.
4. Gravitational folds
These are those wrinkles that appear naturally with age as our skin loses firmness and starts to fold and sag
Where do they Appear?
Gravitational folds appear mostly in the face and neck area, especially where skin and bone density is lost due to age. Leaner faces will tend to make this kind of fold more apparent.
What Causes them?
Age, gravity and time are the main culprits. As we grow old, the skin loses volume and collagen, giving way to sagging skin which causes this type of wrinkle.
How to fight them?
- Intense anti-aging serums, hydrating creams, and beauty protocols, proven to improve firmness and elasticity are indispensable to reduce and reverse the appearance of this kind of wrinkles.
- New cellular extracts such as RxG302™ are now available in the USA. they have the ability to condition the skin at a cellular level, promoting the natural production of Collagen, Laminin and Fibrillin, while improving the cell’s ability to absorb the benefits of other anti-aging ingredients. Products with this kind of technology, like RxGenesys have already shown remarkable results in scientific clinical studies.
- As skin starts to lose volume and fold, the use of dermal fillers can help compensate for such loss, creating volume and making gravitational folds less apparent.
In Summary
When it comes to wrinkles, prevention and maintenance is the key to having and keeping a young and healthy looking skin.
The not-so-good news... Technology has not yet found a way to completely stop wrinkles from appearing or entirely erasing them once they are visible.
The great news... New technologies like cellular extracts (RxG302, ChoNOline and ElixIR) now allow us to significantly reduce the appearance of wrinkles NO MATTER THE AGE.
Dr. Jeffrey Gibson, an American plastic surgeon specialized in cell regeneration & rejuvenation and co-founder of RxGenesys, is the first doctor to put together in one daily beauty routine, all the recommended ingredients to target the different types of wrinkles and sagging skin. Additionally it's surprisingly affordable and is clinically tested.
As a plastic surgeon, Dr Gibson believes in making decisions based on scientific data and proof. That’s why (unlike other companies) we make our complete clinical study reports available for anyone to see on our website (https://rxgenesys.com/pages/results):
RxGenesys is proven to:
- Reduce the appearance of wrinkles by 53% in 2 months
- Improve firmness and elasticity by 43% in 2 months
- 100% of participants noticed a visible reduction in their fine lines and wrinkles